Abstract
In order to observe minute changes of liver surface, a highly magnifying peritoneoscope (Fig. 1, 2, Table 1), whose magnifying power was 100 times, was newly devised and studied about its usefulness in normal and cirrhotic rat liver. On the surface of normal rat liver, this highly magnifying peritoneoscope clearly revealed the status of terminal portal veins (Fig. 4) as well as the sinusoids and liver cell-plates arranged in a radiating fashion (Fig. 5). On the other hand, on the surface of cirrhotic rat liver, more numerous portal veins were seen and most of them appeared to be narrowed (Fig. 19), interrupted (Fig. 14) or stretched (Fig.15). Furthermore, normal arrangement of the liver cell-plate was lost and thickening of cell-plates (Fig.20) were diffusely seen. The number of sinusoids extremely decreased. The experiences mentioned above may signify that this highly magnifying peritoneo-scope may well demonstrate minute changes in various liver diseases.