Abstract
Among 3, 141 cases of endoscopic examinations experienced in the past 5 years at Kyoto National Hospital, 2, 340 cases with abnormal changed were studied clinically and histopa-thologically. The results were as follows : 1) Thirteen percent of all the gastric lesions were seen in the antrum. 4.4 % of all the benign ulcers, 18.2 % of all the gastric cancers and 72.1 % of all the gastric polyps were in the antrum. 2) Of all the lesions in the antrum, 35.6 % were cancers, 35.0 % were polyps and 18.8 % were benign ulcers. 3) The ratio of benign and malignant ulcerative lesions was 2 : 3 in the antrum. 4) In the antrum, 35.7 % of benign ulcers were multiple, whereas in the other part of the stomach it was only 10.1 %. 5) The ages of the highest frequency were their thirties in benign multiple ulcers, fifties and sixties in benign single ulcers and advanced cancers, respectively. 6) Eighty percent of patients with benign ulcer complained abdominal pain as an initial symptom. 25 % of patients with early gastric carcinoma had no complaint. 7) Fifty-six percent of benign multiple ulcers were diagnosed erroneously as malignat at the first X-ray examination, but the diagnoses made by gastroscopies were correctin 83.3 %. 8) All of 9 cases with benign single ulcer had complicated systemic diseases. This may indicate that the systemic disorders per se or administered drugs for them related to the pathogenesis of the antral single ulcers. 9) By taking biopsies from the definite four points, the distribution of intestinal metaplasia was classified into five types. 93% of benign antral ulcers developed in cases of "non-metaplastic" type. Malignant ulcers in the antrum seemed to be closely related to intestinal metaplasia. 10) Ten cases of resected specimens with benign ulcers were histologically examined. Two cases of single ulcer showed the histological features compatible to the "channel ulcer". Six cases of multiple ulcers in the antrum showed characteristic findings of the acute ulcer.
