1979 Volume 21 Issue 9 Pages 1094-1101
In the past 10 years, 116 cases of ulcerative colitis were experienced in the Institute. Six cases among them (2.6%) were three different family pairs. These three family pairs were made up of a parent and an offspring respectively. They suffered from the disease one after the other at an interval of two to five years while living in the same house. The entire large bowel was involved in two pairs. There was no consanguineous marriage in all the paris. One of the three family Paris was examined on HLA typing, but no significant information was obtained so far. The letters of inquiries on the health of other family members were sent to all the other 107 patients, to which 65 patients (about 60%) replied. There was no additional definite familial ulcerative colitis, but four patients (6.1%) stated that some members of their families had expeienced bloody mucous stools of unknown etiology. This may suggest that the actual incidence of familial ulcerative colitis might be a little higher.
