1979 Volume 21 Issue 9 Pages 1111-1116_1
A 27-year-old female with staphylococcal enterocolitis following oral administration of AB-Pc was reported. She was treated with AB-Pc for watery diarrhea (2-3 stools per day) and abdominal pain, which disappeared temporally. Seven days later she was admitted because of bloody mucous diarrhea (7-S stools per day) and lower abdominal pain. The stool culture on admission was positive for Staphylococcus aureus. Endoscopic examination of the colon disclosed multiple erosions, shallow ulcers and reddened spots scattered from the sigmoid colon 30 cm far from the anus, to the mid portion of the ascending colon. The mucosa of the caecum was reddish without erosions and no abnomality was seen in the rectum. Histopathologic study of the mucosal biopsy specimens showed erosions, infiltration of small round cells, Goblet cell depletion, without crypt abscess and eosinophile infiltration. The symptoms disappeared on the 4th hospital day and stool cultures became negative after the fluid replacement therapy, PSL enema and administration of NA. The barium enema taken on the 12th hospital day revealed no abnomal findings in the colon. The roles of the pathological changes seen in the acute stage of the staphylococcal enterocolitis remain unknown. Further studies into this problem are indicated.
