Abstract
A 69-year-old man complaining of right hypochondric pain, hematemesis and melena had underwent an emergency endoscopy 24 hrs after admission. No abnormal findings were noted in the esophagus, stomach and the duodenal bulb. But swelling, redness and bleeding were observed on the papilla of Vater. Furthermore, throughout the second portion of the duodenum were seen redness and erosions associated with bleeding. The acute hem-orrhagic erosions of the duodenal second potion were confirmed histopathologically by biopsy. The reported cases of acute hemorrhagic erosions of the duodenal second portion are extremely few, especially of those cases which were diagnosed endoscopically and histo-pathologically at an acute stage like this. The precise inf ormations in the acute stage would be helpful to study the pathogenesis of such hemorrhagic erosions. This case was also associated with renal failure and we discussed its role.