Abstract
In our routine rectisigmoidoscopic examination, minute mucosal disorders have been noticed not rarely in the rectum by means of the dye-endoscopy. These were classified into 4 types; Type 1, varioliformed mucosal elevations with erosion on each top; type 2, disordered mucosa showing an irregular mucosal net-work pattern, type 3, sporadic small mucosal depressions; type 4, variformed low mucosal protrusions. Although it may be speculated that these disorders might be caused from proctitis due to infections or acute inflammatory diseases, it is difficult to study the pathogenesis retrospectively. So, the fol-low-up stusy of 3 cases of aphthoid colitis and a case of pseudomembranous colitis have been made prospectively. Type 1 was seen in the acute stage of aphtoid colitis, which became smaller and lower a week, later and then, type 3 was seen a month later. Biopsy specimens taken from the type 1 disorders which were seen a week later, showed lympho-follicular proliferation in the submncosa. These changes, however, were not observed in the type 3. On the other hand, mucosal disorders of type 4 were seen continuously for 6 months in a case of pseudomembranous colitis. Biopsy specimens also showed lymphofollicular proliferation in the submucosa. Magnifying observation by using CF-HM was a useful method to observe the details of the disordered mucosal surface. For the study of the pathogenesis of these disorders, it is necessary to continue the follw-up study of other kinds of proctitis.
