Abstract
This report described a case of 52-year-old female patient with pernicious anemia com-plicating gastric cancer and hypothyroidism. She was diagnosed to have pernicious anemia 11 years ago at Asahikawa Municipal Hospital, and had been followed up with X-ray and endoscopic examination annually until 3 years ago. She was admitted to our hospital because of general fatigue and upper abdominal pain. Gastroendoscopic examination revealed a Borrmann II type tumor on the greater curvature of the upper gastric body, which was subsequently confirmed by biopsy as poorly differenti-ated adenocarcinoma. Furthermore, laboratory findings showed hypothyroidism and microsome test was 6402 dils positive. In the past history, she had been diagnosed to have Graves' disease, treated with antithyroid drugs our presumptive diagnosis was Hashimoto's thyroiditis as a cause of hypothyroidism. The autoimmune mechanism was therefore assumed to be responsible for this case. We reported here a rare case of pernicious anemia associated with gastric cancer and hypothyroidism.
