1982 Volume 24 Issue 2 Pages 265-268_1
An argon laster light (Power: 300mW, Wavelength: 488nm) induced an autofluorescence in the human and rat hepatocellular carcinomas, when observed with a filter which transmitted the light of wavelength over 520nm. In human hepatocellular carcinoma, an autofluorescence was observed heterogeneously, strongly in some parts and compelely not in other parts of the liver with carcinoma. When observed with the day light, the former was identified as the part of hepatocellular carcinoma, whitely yellowish in color, and the latter as a necrotized part, dark black in color. In rat hepatocellular carcinoma, on the other hand, a yellowish autofluorescence was observed almost homogeneously on argon laser light irradiation. When observed by the day light, the part of hepatocellular carcinoma was hemogeneously white in color. The findings were samely observed both on the liver surface covered with paritoneal capsule and the cut surface of the cross section. The autofluorescence phenomenon induced by an argon laser light would be an useful supplemental method for the laparoscopic diagnosis of the hepatocellular carcinoma.
