1982 Volume 24 Issue 2 Pages 316-322_1
Only 20 cases of colonic carcinoma with tuberculosis have been reported so far in Japan. A case of carcinoma of the ascending colon and cecum associated with old bowel tuberculosis was described. A 74-year-old female was addmitted to our hospital on Oct. 30, 1978, complaining of the ileocecal mass with pain. Chest X-P showed a calcification in the right upper lobe of the lung. Culture of the feces and biopsy specimen were negative for T. B., Barium enema and endoscopy including biopsy demonstrated malignant villous tumor of the ascending colon and cecum. The lesion of the operated specimen, measuring 10.5×7.8cm, macroscopically showed the villous surface. Histological findings disclosed a well differentiated adenocarcinoma, showing a villous and tubulo-villous feature in the surface. Moreover, several granulomas close to the carcinoma in the colonic wall, consisting of Langhans' giant cells, epitheloid cells and lymphocytes, were seen. And the same glanulomas with central caseation in the lymph nodes were also seen. Therefore, this case was regarded as an association with colonic carcinoma and old tuberculosis.