GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
GIANT GASTRIC ULCER SHOWING PROTRUDING CHANGE ON ITS HEALING PROCESS BY NEW H2-RECEPTOR ANTAGONIST : REPORT OF A CASE
Yuichi SASAKI[in Japanese]Hideaki YAMADAEiji MITANITeisuke KAMATATokio ONOKenzo KOBAYASHISukeo YAMAMOTO
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1982 Volume 24 Issue 9 Pages 1413-1418_1

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Abstract
This is a presentation of a case with a giant ulcer showing the protruding change on its healing process.The patient was 59-year-old male who was admitted to our hospital with chief complaints of severe epigastric pain and hematemesis. X-ray and endoscopic examination of the stomach revealed a giant ulcer on the posterior wall of the gastric angulus.After four weeks of treatment with a new H2-receptor antagonist (Ranitidine), this lesion changed a whitish protrusion without regenerated epithelia. Histologically, it showed granulation tissues with marked increase in capillaries and distinct infiltration of lymphocytes.Subsequently, we observed endoscopically biweekly, and we found that this protrusion had disappeared after twenty-one weeks of treatment.
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© Japan Gastroenterological Endoscopy Society
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