Abstract
This is a presentation of a case with a giant ulcer showing the protruding change on its healing process.The patient was 59-year-old male who was admitted to our hospital with chief complaints of severe epigastric pain and hematemesis. X-ray and endoscopic examination of the stomach revealed a giant ulcer on the posterior wall of the gastric angulus.After four weeks of treatment with a new H2-receptor antagonist (Ranitidine), this lesion changed a whitish protrusion without regenerated epithelia. Histologically, it showed granulation tissues with marked increase in capillaries and distinct infiltration of lymphocytes.Subsequently, we observed endoscopically biweekly, and we found that this protrusion had disappeared after twenty-one weeks of treatment.