Abstract
Rat experimental ulcer is very often used to examine the biological effects of many anti-ulcer drugs. We attempted to obtain a detailed picture of gastric mucosa in rat. The gastroscope is mainly used in large animals such as dogs, and is not used in small animals such as rats. Recently a few reseachers use a bronchoscope in rats. Bronchoscope is small in diameter, and does not provide a detailed picture of rat gastric mucosa. In this study, using a human gastroscope, we could take detailed pictures of gastric mucosa in rats with gastric fistula. This method is very useful for studying the experimental ulcer in the rat.