1983 Volume 25 Issue 12 Pages 1981-1985
A 65-year-old male with transurethral resection for a bladder tumor received anti-microbial chemotherapy such as CET i. v., DKB i, m., and PPA p. o. after operation. He developed high fever and watery diarrhea, ten times a day on the third day of operation. Clostridium difficile was isolated from his stool, and endoscopic findings showed pseudomembranes in the rectum, so he was diagnosed to have pseudomembranous colitis. Then all the anti-microbial agants were discontinued and Metronidazole was admini-strated. After a week of treatment the diarrhea and fever subsided. On the 14th day of therapy no C. difficiles could be isolated, but pseudomembranes were still seen in whole areas of the rectum, endoscopically disappeared on the 46th day of therapy. Our case suggests the discrepancy between the clinical course and endoscopic findings, and it may be important to follow up them endoscopically even after all the symptoms have subsided and laboratory Batas have normalized.