Abstract
A comparative study was made on biopsied specimens of depressed type early gastric cancer of 79 caces, 84 lesions. Each biopsy specimen was obtained after conventional, dyescattering and magnifying endoscopic examination. Comparison among these three techniques was made on positive ratio. Results were as follows. 1) An average positive ratio by conventional endoscopic examination was 65.0%. Each positive ratio of the specimens from discolored area and reddened area was 71.3% and 59.1%, respectively. Histologic examination revealed that most of the biopsied specimens from reddend area were well differentiated adenocarcinoma and most from discolored area were poorly differentiated adenocarcinoma. 2) An average of positive ratio by dye scattering method was 84.9%. This was significantly higher (p<0.001) in comparison with that by conventional endoscopy. 3) An average 300153_002of positive ratio by magnifying endoscopy was 81.3 % and was significantly higher (p<0.01) compared to that by conventional endoscopy. Each positive ratio of the biopsied specimens obtained from the mucosa characterised by patternless mucosal appearance, nodular mucosal appearance and irregular nodular mucosal appearance was 95.5%, 76.8%, and 82.2%, respectively.