Abstract
A 16-year-old female was admitted to the Kanazawa Medical University Hospital because of pain on the right hypochondrium. The double contrast X-ray picture of the duodenum revealed many small polypoid lesions with coarsely widened mucosal folds and reflux of contrast material into the pancreatic duct. On the endoscopic examination of the duodenum, several sizes of polypoid lesions were seen on the duodenal mucous membrane. The orifice of the duodenal major papilla was kept open and a continuous flow of the bile was observed during the examination. Histological changes of biopsy specimens from the duodenal mucosal epithelium were minimal except for infiltration of a few inflammatory cells in the interstitial space. Since she was one-year old, the patient has had many recurrent episodes of bronchitis and pneumonia. Numerous reticulo-nodular shadows were seen at both lung fields of the chest X-ray film. Labial minor salivary glands showed dilatation of the ducts, accumulation of mucin, and atrophy of acinal cells. Sodium and chloride concentrations of the sweat increased markedly.
