1984 Volume 26 Issue 11 Pages 1942-1946_1
A case of superficial exfoliation of esophageal mucosa associated with pemphigoid was seen and endoscopic examinations were performed before and after immunosuppressive therapy. The case is a 45 year old woman who was admitted to the hospital because of nausea followed by hematemesis and an emesis of string formed whitish material. Endoscopic examination revealed well demarcated circular, reddish mucosal defect locating in esophagus about 33cm from the dental arch. The oral side of this lesion appeared to be normal but easily exfoliated by biopsy forceps leaving well demarcated reddish discoloration. Electron microscopic examination of the mucosa was made and findings were reported to be identical with the diagnosis of pemphigoid. Predonisolone 30mg and endoxan 50mg per day were given and after this treatment the above mentioned esophageal changes disappeared. The superficial exfoliation of esophageal mucosa, like in this case, can be a part of pemphigoid, and the immunosuppressive treatment was thought to be effective.
