1984 Volume 26 Issue 12 Pages 2421-2425_1
This is a case of Menetrier's disease accompanied by Buerger's disease and multiple lipomatosis. Patient was 34-year-old male and referred to the Osaka Medical College for further evaluation of hypoproteinemia detected during the treatment of Buerger's disease. Physical examination revealed numerous lipomas on the trunk and upper and lower extremities. Laboratory findings showed hypoproteinemia and hypoalbuminemia. Loss of protein from the gastrointestinal tract was confirmed by the result of 131I-RISA and 125I-PVP test . Electrophoretic pattern of the gastric juice was similar to that of serum protein. Huge, convoluted gastric rugae were found throughout the entire fundus and body of the stomach by both x-ray and endoscopic examinations. Histology of gastric biopsy showed mucosal hyperplasia. Gastrectomy was performed under a diagnosis of Menetrier's disease. Serum protein, albumin, 131I-RISA and 125I-PVP improved one month following the operation.
