Abstract
Three hundred patients with diabetes mellitus (insulin dependent) were investigated on peptic ulcer, and compared with three hundred non-diabetic subjects without gastrointestinal problems, all who were hospitalized at about same time. In the latter, patients who had either liver or pancreatic disease were excluded because of the possibility of their gastrointestinal involvement. The incidence of peptic ulcer in diabetics was 5%, and the same rate as those in non-diabetics. Out of 300 subjects with diabetes mellitus, 6 patients with gastric ulcer (s), 8 patients with duodenal ulcer (s) and 2 patients with gastroduodenal ulcers were found, but there were no characteristic features endoscopically. Peptic ulcer was more commoncy found in patients with neuropathy than those without it. Active ulceration was more predominant in patients with poorly controlled diabetics. In conclusion, these results indicate that there is no difference on the incidence of peptic ulcer and its clinical features between diabetics and non-diabetics.
