CARCINOMA OF THE DUODENAL PAPILLA IN A YOUTH

Abstract

A 25-year-old man was admitted to Jichi Medical School Hospital, complaining of poor appetite and general fatigue. Laboratory examination on admission showed liver dysfunction and elevation of amylase activity in both serum and urine. When ERCP was performed, a mass protruding into the lumen with a central small depression was found endoscopically in the region of the duodenal papilla. Endoscopic biopsy showed signet-ring cell carcinoma and the tumor was resected surgically, ranging 4 X 2.5 X 0.8cm in size. A central small depression of the tumor connected with the common duct. Age distribution of 413 cases reported on literature during the last ten years was studied. Cases in their twenties as our patient are very rare. Signet-ring cell carcinoma is extremely rare in cases of carcinoma of the duodenal papilla.