FOLLOW-UP STUDY ON FUNDAL GASTRITIS AND INTESTINAL METAPLASIA BY THE ENDOSCOPIC CONGO RED-METHYLENE BLUE TEST

Abstract

The development and extension of fundal gastritis and intestinal metaplasia were investigated by the endoscopic Congo red-methylene blue test in 44 healthy subjects, 106 patients with gastric ulcer and 26 patients with gastric polyp. Follow-up chromoendoscopic examinations were made an average of 3.4 years (110 years) after the initial endoscopicassessememt. Among healthy subjects, the development and, or extension of fundal gastritis and of intestinal metaplasia were only found in 3 (6.8%) and 2 (4.5%), respectively, and the development and extension of these changes may require time. In patients with gastric ulcer and in those with gastric polyp, fundal gastritis and intestinal metaplasiadeveloped or extended significantly more frequently and more rapidly than in healthy subjects. Fundal gastritis and intestinal metaplasia extended with time mainly in an upward direction.