Abstract
A diagnostic rate of the depth of invasion of gastric cancer based on endoscopic findings was 78% in the elevated lesions, 56% in the depressed lesions and 59% in the total cases. Therefore, investigation of the depth of invasion of gastric cancer through submucoso graphy was carried out. Investigation of a contrast medium as well as its association to a surfactant agent was also carried out in canine. As the result, Myodil seemed to be the most appropriate as the contrast medium. Furthermore, a tendency of spreading of the contrast medium and the relation between the radiological features of submucosography and the histological depth of invasion were also investigated in 36 clinical cases. Through the radiological features of spreading of the contrast medium, the following classification was made : type A at the frontal view-when there was no restriction of the spreading (type A' at the lateral view), type B at the frontal view-when there was a partial restriction of the spreading (type B' at the lateral view) and type C at the frontal view-when there was total restriction of the spreading (type C' at the lateral view). Histologically, the type A indicated to have the depth of invasion within m, the type B down to sm and the type C deeper than pm. The diagnostic rate of the depth of invasion by this method was 75%. Moreover, the diagnostic rate with combination of submucosography and the endoscopic findings was 81%. Consequently, submucosography is thought to be a useful method in the diagnosis of the depth of invasion of gastric cancer.
