Abstract
A 61-year-old male with liver cirrhosis who was persistently positive for hepatitis B surface antigen (also positive for HBeAg) was found to have a small liver cancer in the right lobe of the liver under peritoneoscopy. No mass was detected by various imaging methods including echogram, computed tomography, scintigram and hepatic arteriography. Intravenous injection of ICG at the dose of 5 mg/kg was administrated for the purpose of clearly observing the tumor and surrounding cirrhotic nodules. 25 minutes after the dye injection, the liver surface were stained green, while the tumor parenchyma and the small blood vessels surrounding the tumor were not stained at all. The partially encapsulated tumor with 9 mm in diameter was enucleated. Histological examination of the specimen revealed highly differentiated tubular adenocarcinoma (Edomondson II) of the liver. A combination of ICG dye administration and guided liver biospy during per-itoneosocpy might help to diagnose a small iver cancer.
