Abstract
We experienced 21 patients with goose flesh-like mucosa of the stomach and conducted clinical, histological and immunohistological studies. Females comprised 57.1% of all patients; 81% aged from 10 to 29. Concerning the clinical symptoms, 52.4% of the patients had epigastralic pain and some had nausea and vomiting. Numerous granular small elevations were observed in the pyloric gland region by roentgenological examination. Uncountable small elevations appearing goose flesh were seen by endoscopic examination. Dye spraying endoscopy with Indigocarmine revealed more elevated lesions, compared with normal area gastrica of pyloric gland and made the surface clear. C0 and C1 types of the mucosal border of the stomach comprised 90%. Histological findings showed hyperplasia of the foveolar epithelium, but atrophy of pyloric glands was rarely seen. Lymph follicle formation was frequently seen in the propria mucosae. This lesion could be differentiated from follicular gastritis of the atrophic type as defined by Yoshii or Morson. Goose flesh-like mucosa of the stomach was thought to be follicular gastritis of the hyperplastic type. Some cases showed a strong stain of IgA and positive tendency of SC in the lumen of pyloric glands by immunohistological study.
