Abstract
A case of gastric hyperplastic polyposis associated with three early polypoid cancers was described. The patient was a 56-year-old male. He came to our hospital on October 11, 1984. Radiographic and endoscopic examination revealed numerous polypoid lesions in the stomach (Figure 1, 3). Histological examination of endoscopic biopsy from some polyps showed hyperplastic polyps with no evidence of malignancy. Total gastrectomy was performed on January 10, 1985. Macroscopic findings of the resected specimen showed thirty-nine polyps from the upper body to the angular region (Figure 4). They varied in shape from Yamada's classification I to IV and measured 2-20 mm. in diameter. Histologically, all of the polyps were diagnosed as foveolar hyperplastic type except for three polypoid cancers. These cancerous lesions were located on the lesser curvature (12 x 7 mm. in size), the posterior wall (5 x 4 mm.) and the greater curvature (7 x 6 mm.) of the angular region respectively and composed of papillary adenocarcinoma without any metastasis (m, no, ly (-), v (-)) (Figure 5, 6, 7). The three polypoid cancers were not distinguishable from the other hyperplastic polyps endoscopically and it was practically impossible to get biopsy specimens from all of the polyps. Accordingly surgical treatment should be taken into consideration in cases of gastric polyposis such as the one presented here.