TWO CASES OF THE GASTRIC ADENOSQUAMOUS CELL CARCINOMA DIAGNOSED BY GASTROSCOPIC BIOPSY

Abstract

Two rare cases of adenosquamous cell carcinoma of the stomach diagnosed by gastroscopic biopsy have been reported. Case 1: A 67-year-old man was admitted to our hospital with complaints of epigastralgia and bloody stool on May 1981. Roentgenographic and endoscopic studies showed Borrmann's type 2 carcinoma at the antrum. Histological examination of the biopsy specimens revealed squamous cell carcinoma and well differentiated adenocarcinoma. Histological findings of the resected specimens of the stomach showed advanced cancer, measuring 4 × 5cm invaded into the serosa (se). No metastatic lesion of the regional lymph nodes was noted. He still lives at five years after surgery. Case 2 : A 72-year-old woman was admitted to our hospital with complaints of epigastric discomfort on May 1982. Studies of upper G. I series showed carcinomas of Borrmann's type 1 and type II a at the antrum. Microscopically, biopsy specimens revealed squamous cell carcinoma and poorly differentiated adenocarcinoma. The histological findings of the resected stomach revealed an early cancer (type I + II a), measeuring 3 × 2.5 cm invaded into the submucosa (sm). However, there was a regional lymph nodes metastasis(n3 +). Surgical treatment resulted in absolutely non-curative operation. She died in 7 months after surgery.