GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
ENDOSCOPIC LOCAL INJECTION OF AETHOXYSCLEROL TO UPPER GASTROINTESTINAL BLEEDING
Hitoshi OKANOHiroshi NISHIDAMasayuki IMAMURAHideichi UCHIDAYuichi HORIGUCHITatsuyuki SATOHToru OHISHIKyohei MARUYAMATadashi KODAMATatsuro TAKINO
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1986 Volume 28 Issue 6 Pages 1233-1236_1

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Abstract

Several endoscopic methods have been applied to the upper gastrointestinal bleeding. The present report describes a new method, using Aethoxysclerol, of treating upper gastrointestinal hemorrhage endoscopically. Aethoxysclerol commonly used as sclerosant of sclerotherapy, was applied to arrest hemorrhage from the upper gastrointestinal tract. At first fundamental effect of local injection of Aethoxysclerol solution was evaluated using the dog. It was recognized that effect of injection was due to compression of vessels by edema of stroma and microthrombosis and late effect was due to formation of thrombo-sis by endvasculitis. In clinical use, Aethoxyscleral was injected circumferentially to a total of 3-4 ml beneath the base of bleeding lesions. In 13 of 15 cases, this procedure had a definite benefit for the patient and no complication occured. It was concluded that local injection of Aethoxysclerol was safe and an effective method for the hemostasis of upper gastrointestinal bleeding.

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© Japan Gastroenterological Endoscopy Society
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