1986 Volume 28 Issue 7 Pages 1553-1561
Out of the 292 cases of scirrhous carcinoma of the stomach resected at the National Cancer Center Hospital from 1962 to October, 1981, 241 underwent endoscopic examinations prior to surgery. Out of them, five cases (2.1%) were endoscopically incorrectly diagnosed as early gastric cancer. Another case was wrongly diagnosed as early gastric cancer found to be scirrous carcinoma of the stomach at the time of surgery for esophageal cancer. There are 13 cases followed-up endoscopically. From the analysis inclusive of all above 19 cases, the growth of scirrhous carcinoma of the stomach is considered as follows ; (1) The period of distensable state of gastric wall before rigidity ensues is relatively brief. (2) The rigidity of the gastric wall widespread within a remarkably short period of time. Considering the mechanism of this change, we have to think about the role of some kind of inducer which functions as a trigger rather than the quantity of collagen or fibrosis.
