Abstract
To evaluate the incidence of recurrence of duodenal ulcer (DU), dyeing endoscopy in combination with methylene blue (MB) and congo red (CR) were performed in 150 patients (pts) with DU scar. MB absorption divided duodenal mucosal regeneration pattern into 3 groups as follows ;Group A : poor absorbing, Group B : fair absorbing, Group C : good absorbing, CR discolored pattern was categolized into 4 types as follows ;Type I : discolored border at the gastric angle, Type II: discolored border at the gastric middle corpus, Type III: discolored border at the gastric upper corpus, Type IV : so called "open type".Results : Retrospective study : There were 47pts (31%) in group A, 8lpts (54%) in group B, and 22pts (15%) in group C. Conversely, 44pts (29%) were in type I, 57pts (38%) were in type II, 36pts (24%) were in type III, and 13pts (9%) were in type IV.Group A consisted of 55% of type I, 32% of type II, 13% of type III, 0% of type IV, while Group C consisted of 9% of type I, 32% of type II, 41% of type III, and 18% of type IV. Out of 80pts who had the recurrence of DU in the past, 32pts (40%) were in group A, 42pts (52.5%) were in group B, and 6pts (7.5%) were in group C. Prospective study : A total of 110pts were followed up prospectively for a mean of 12.4±5.9 months (1-20 months). There were 29pts (26%) in group A, 62pts (57%) in group B, 19pts (17%) in group C, while 34pts (31%) were in type I, 43pts (39%) were in type II, 23pts (21%) were in type III, and l0pts (9%) were in type IV. Out of 110pts, 22pts (20%) had the recurrence of DU. The recurrence rate was 44.8% in group A, 41.2% in type I, and 57.9% in both group A and type I. Conclusions : In our study population, pts who belonged both in group A and type I at the same time, had higher recurrence rate of DU. It is concluded that dyeing endoscopy with combination MB and CR appeared to be effective for detestation of the recurrence of DU.
