SEQUENTIAL LAPAR.OSCOPIC AND ULTRASONOGRAPHIC OBSERVATIONS OF THE LIVER IN A CASE OF WILSON'S DISEASE TREATED WITH D-PENICILLAMINE

Abstract

We reported a 34-year-old patient with Wilson's disease. Although he presented neurological manifestations on admission, they disappeared after treatment with D-penicillamine. Before treatment, ultrasonographic finding showed multiple hyper-echoic and hypo-echoic space occupying lesions in the liver. Peritoneoscopic picture showed various sizes of yellowish or dark brown degeneration nodules in the liver. Biopsy specimen revealed remarkable fat and copper deposits in the liver. After treatment with D-penicillamine, ultrasonographic finding of the liver turned to be normal. Peritoneoscopic picture showed flattened nodules of the liver and yellowish or dark brown color was reduced. Fat or copper deposits of biopsy specimen were also markedly reduced.