Abstract
The thermal diffusion method for measurement of canine gastric mucosal blood flow (GMBF) at laparotomy has been described previously. In this report, the continuous measurement of GMBF under endoscopic observation by thermal diffusion method was attempted. The authors used newly designed cathether-type probe (Figure 1). Suction pressure applied to the tip of this probe allows good attachment of the probe surface to the gastric mucosa, and stable measurement value was obtainable under endoscopic observation. For the purpose of estimating the reliability of this thermal diffusion method in measuring GMBF, changes of GMBF accompanying the intravenous infusion of AOC tetrapeptide (gastrin), vasopressin, and KCl (140meq) were examined by continuous monitoring of voltage difference, which is measured value of thermal diffusion method. The results obtained, reflected the expected changes of GMBF during these procedure (Figure 6, 7, 9, 11), and this thermal diffusion method correlated well with the electrolytical-ly generated hydrogen gas clearance method (correlation coefficient 0.93 : p 0.01 Figure 12 B).
