Abstract
A 75-year-old female was admitted to our hospital complaining of high fever and general fatigue. On the laboratory findings, marked eosinophilia and liver dysfunction were pointed out. No parasite egg was detected in the duodenal juice and in the feces. Liver scan with 99mTc revealed an irregular isotopic accumlation in the left lobe. Ultrasonography showed the hypoechoic lesion on the ventral side of the left portal vein. Computed tomography disclosed several small low density areas in the left lateral segment of the liver. By the laparoscopy, the thickened liver capsule on the right lobe, solitaly or fused yellowish white nodules on the ventral surface of the left lobe were seen. Liver biopsy was performed from the nodules, and the histological examination showed necrosis of liver tissue, infiltration of eosinophils and the presence of numerous Charcot-Leyden crystals surrounded with granulation. The diagnosis of hepatic fascioliasis was confirmed by positive serological test. She was given Praziquantel (1800 mg/day) for one day, with rapid resolution of clinical symptoms and labolatory findings.
