GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
CLINICAL COURSE OF CROHN'S DISEASE
—CHRONOLOGICAL CHANGES OF LESIONS OF THE LARGE INTESTINE—
Ei SASAKINorito MATSUKUMAHideo IKEDASaburo KAMOIReiichiro HIDAKARintaro INOUEKazuhiro OOMAGARIToru MINAMITakashi UETAHiroshi IKEZONO[in Japanese]Tadashi FUZIMIAtsushi TOYONAGATadahiko KUNISAKIKyuuichi TANIKAWAHiroharu ISOMOTO
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1987 Volume 29 Issue 6 Pages 1187-1195_1

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Abstract
12 patients with Crohn's disease suffering for more than five years were investigated concerning the changes of colonic lesions by X-ray and endoscopic examinations. The results obtained were as follows. 1. When the medical treatment was effective, multiple small ulcers and aphthoid ulcers disappeared and changed to a localized cobblestone appearance. 2. Cobblestone appearance, which were recognized on the initial study, improved to coarse inflammatory polyps. However, some of them exacerbated to dense inflammatory polyposis with a stenosis. 3. Longitudinal ulcers which were found on the initial study, remained unchanged for a long period, or altered to an eccentric deformity. 4. These results suggested that the early lesions of the large intestine were multiple small ulcers and aphthoid ulcers.
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© Japan Gastroenterological Endoscopy Society
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