Abstract
A 37-year-old unmarried man complained epigastralgia, vomiting and anorexia. X-ray examination showed narrowing of the antrum with granular appearance of the anglus mucosa. Gastroscopic examination showed multiple shallow small ulcers of the antrum and anglus, which were surrounded with easily bled and thickened mucosa. Although the upper gastrointestinal study initially raised a suspicion of gastric lymphoma, gastric biopsy showed intense mononuclear infiltration with no evidence of malignancy. Based on positive result of serologic test for syphilis and characteristic X-ray and endoscopic findings, gastric syphilis was strongly suspected. After 4 weeks of anti-leuetic therapy with peros erythromicin 1200 mg/day and anti-ulcer agents with a H2-blocker, epigastric pain was relieved and the lesion healed completely. Biopsy of the stomach after the treatment revealed no cellular infiltration.
