GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
TWO CASES OF DRUG-INDUCED PANCREATITIS DUE TO METHYLDOPA AND MEPHENAMIC ACID
Tetsuji AKIYAMATadasu FUJISatoshi KONDOHKayoko ADACHIShinya TANAKAKenzoh HARIMAToshiyuki SASAKIRyohsuke OHMURAKazutaka NAKATATakayoshi NOGUCHIHideo AMANOTsuyoshi AIBETakayoshi TAKEMOTO
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1988 Volume 30 Issue 4 Pages 760-765_1

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Abstract
We experienced two cases of drug-induced pancreatitis. The first case caused by methyldopa was proved by challenge test, and the second case by mephenamic acid was proved by lymphocyte stimulating test. The former developed epigastric pain associated with hyperamylasemia, and the latter presented with frequent vomiting after meal. These symptoms were similar to those of alcoholic pancreatitis. Nine cases of methyldopainduced pancreatitis have already been reported in the world. On the other hand, mephenamic acid has not been previously reported as a cause of pancreatitis.
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© Japan Gastroenterological Endoscopy Society
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