Abstract
Endoscopic polypectomy followed by sigmoidectomy was performed in the case of sigmoidal polyp because the pathologic examination revealed massive invassive submucosal cancer. Resected specimen showed local formation of granulomatous polyp. Since mucosal repair after polypectomy is usually accomplished by scarring, restoration with protrusive granulation tissue seemed relatively rare. Cases of polypectomy followed by colectomy were 29 cases (33 lesions) at our institute. We examined the repair of mucosa on 33 lesions and the following results were obtained. # 1: Acute ulcer was noted at the site of polypectomy when colectomy was performed within 10 days after polypectomy. Ulcer formation was not related with the presence or absence of residual cancer. At around 20 days, ulcer entered healing stage and ac-companied with slight mucosal convergence. # 2 : At around 30 days, contraction due to ulcer scar become marked and mucosal convergence was completed. After 30 days almost ulcer was healed and mucosal defect was repaired. # 3 : In cases where the defect was coverd with granulation or regenerative epithelium. They showed flat depressive lesions. # 4 : Except for regrowth of cancer, 2 protrusion occurred in the course of repair consisted of hyperplastic regenerative epithelium and consisted of exuberant granulation. It took more than 30 days after polypectomy to form these protrusions. # 5 : Formation of granulomatous polyp seemed to involve exuberant granulation at the site of defect during 2 to 3 weeks after polypectomy and formation of a protrusion during 4 to 7 weeks. Exuberant granulation sometimes occurred at the site of intestinal anastomosis, but it is rare after endoscopic polypectomy.
