1988 Volume 30 Issue 6 Pages 1213-1217_1
Between January 1970 and April 1987, we treated 186 cases of early gastric cancer. Twelve among 186 cases (6.45%) had early gastric cancer associated with primary malignant neoplasms of the other tissues or organs, and they were determined as multiple primary malignant disease according to the criteria of Warren and Gates. The patients with multiple primary malignant disease were significantly older than the patients with earely gastric cancer only (mean age : 69.9 y.o. vs 61.6 y.o. ; p<0.01) and 10 patients were male (male : female =5:1). Eight patients had lesions that were diagnosed simultaneously and 4 patients had lesions that were diagnosed at intervals of more than one year. Four of 12 patients (33.3%) associated with esophageal cancer and 8 of 15 lesions of the associated malignant neoplasms (53.3%) occurred in digestive organs. Their prognosis was dependent on that of the associated malignant neoplasms. Fiveyear survival rate was 16.7 per cent and the average survival period was 22.7 months. The case of early gastric cancer associated with primary malignant neoplasms is not so common, but their prognosis may become very bad when accompanied with other malignant neoplasms. Therefore, treating with old patients of early gastric cancer, the other organs, especially digestive tract, should be precisely examined.
