GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
EXPERIENCE WITH NEWLY DEVELOPED POLYETHYLENE GLYCOL ELECTROLYTE LAVAGE SOLUTIONFOR PREMEDICATION AT COLONOSCOPY
Tadayoshi TAKEMOTOTakashi HARIMATaeko MiyaharaRyujiro YASUTAKEShinjiro MATSUURAShunji YOSHIMURAKazunari YAMAMOTOKiwamu OKITAYukinori OKAZAKIAkira KOSHIROKeizo ISHIMOTO
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1988 Volume 30 Issue 6 Pages 1291-1296_1

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Abstract

Since Davis introduced lavage solution contained polyethylene glycol electrolyte solution in 1980, lavage solution technique for premedication in case of endoscopic and fluorescopic examination of the colon has been popular particularly in the Western countries. However, it is true that oral administration of polyethylene glycol electrolyte lavage solution (PEG-ELS) between 3, 000 and 4, 000 ml is absolutely necessary for getting a better lavage effect and this large dosage may trouble the patients. Therefore, we have tried to develop new PEG-ELS which show a better lavage effect even in a lesser dose, and the present study was planned to make sure the lavage effect of newly developed PEG-ELS. Sixty subjects ranging from 24 to 77 in age (54.1 in avarage) were used for evaluation. Concerning dosage of this lavage solution, avarage tolerable dose was 2, 782 ml and in the group tolerated to a dose between 2, 000 and 2, 500 ml a sufficient lavage effect was taken. In conclusion, newly developed PEG-ELS showed a sufficient lavage effect in lesser dosage- as compared with original PEB-ELS developed by Davis.

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