Abstract
A 59-year-old woman, who was diagnosed of PBC (Scheuer II-III stage) 6 years ago and followed up without any symptoms, was admitted again to control DM. Laparoscopic and histlogical findings showed remarkable progression of PBC (Scheuer-IV stage), and ERCP showed abnormal findings of pancreatic duct. These abnormalities in pancreatic duct were not seen at the first admission, which suggested that these findings appeared in association with the progression of PBC. We speculated these lesions of pancreatic duct might be due to the same mechanism of PBC lesions in bile ducts. Laparoscopic findings, which showed the typical "rough bigger block" at the first admission, represented fine block formations diffusely. During the follow-up of this case, liver function tests have been stable, icterus has not been seen and itching has been diminished. Nevertheless, PBC lesion of this case progressed to complete liver cirrhosis. This case gave us some suggestion about the course of PBC progression.
