Abstract
A case of gastric syphilis was reported. A 46-year-male patient was admitted to our hospital because of severe epigastric pain and hematemesis. On endoscopic examination, multiple huge ulcers with hemorrhage and mucosal edema in the body and angle were noted (Figure 3-a, b, c, d). These ulcers had no healing tendency despite the administration of H2 -blocker and other anti-ulcer agents (Figure 5-a, b). Since biopsy specimens were negative for malignancy and serological tests for syphilis were positive, gastric syphilis was strongly suspected. After two weaks of anti-luetic therapy with penicillin-G, the lesions began to heal (Figure 6-a) and after nine weaks, completely healed (Figure 6-c, d). Gastric syphilis is relatively uncommon and is difficult to be dif f erenciated from cancer, malignant lymphoma or RLH. If anti-ulcer therapy is not effective, biopsy specimens are negative for malignancy and serological test for syphilis is positive, gastric syphilis should be suspected.
