Abstract
A 65-year-old man, being pointed out multiple gastric polyps 12 years ago, came to our hospital with chief complaint of epigastric discomfort. Upper gastrointestinal examinations revealed the multiple polyps of various sizes on the intermediate zone of the stomach, which were suggestive of Nakamura typeII, and the shallow depression with converging folds among the polyps. Moreover, the polyp near its depression was pale and flattened. Biopsy specimens taken from the shallow depression showed well differentiated adenocarcinoma. Macroscopic view of the resected stomach showed about 70 polypoid lesions of various sizes (3-20mm in diameter), some of which had irregular central depression, and the shallow depression with converging folds on the lesser curvature of the lower body. Histopathologically, early gastric cancer of type IIc+IIa, 25×17 mm in size, was found on the lesser curvature aspect of lower body. IIa part of the lesions showed the polyp cancer. In the antrum, the minute mucosal cancer, 2 mm in size, was found. We reported the case of gastric polyps with multiple early gastric cancers. This case suggests that the stomach with multiple proliferating polyps has the malignant potential.
