Abstract
The extension and progress of atrophic gastritis was studied in order to elucidate the correlation between atrophic gastritis and Campylobacter pylori (C. pylori). The correlation between C. pylori colonization and the extension of an atrophic pattern and intestinal epithelial mataplasia, as well as the significance of C. pylori colonization in the chronological changes of atrophic gastritis were studied. Endoscopic congo red technique and the follow-up examination were performed in 178 patients. C. pylori was indentified in gastric biopsy specimens from the patients. A decrease in the detection rate of C. pylori was seen in C1 or in O3 and O4 in which a more progressed atrophy was noted. A decrease in the detection rate was observed in cases with a wider area of intestinal epithelial metaplasia. The detection rate of C. pylori was high in cases in which the atrophic pattern shifted during the course of follow-up and was significantly lower in cases in which the atrophic pattern did not shift.
