Abstract
From 1971 to 1987, 231 cases of typical acute gastric mucosal lesions (AGML) were treated in Kitasato University Hospital. A clinical and endoscopic analysis of AGML were made, and the results were as follows : (1) The main causes of AGML were drugs (37.7%), emotional stress (24.3%), surgical stress (4.3%) and cerebral disease (5.2%). While in 51 cases there was no inducing factor for AGML. (2) The lesions were most frequently seen in the antrum (43.3%), and 31.2% of the patients were in the upper part of the body. But most of the upper-gastrointestinal tracts were affected widely. (3) Drug induced AGML were found equally in the antrum and upper-body, and AGML induced by emotional stress were located in the antrum. (4) AGML in the antrum were 100 out of 231 cases, and were more frequently sees in younger age. They were consits of acute multiple ulcers and acute erosive gastritis. Lesions of the patients with critical illness were mainly acute erosive gastritis. (5) Acute multiple ulcers in the antrum were seen in 36 cases, out of which 10 cases were drug-induced, 13 cases were induced by emotinal stress, 13 cases were of unknown origin. Acute multiple ulcers healed rapidly and recurrence of ulcers was not seen for more than 3 years in 23 cases.
