Abstract
A 26-year-old unmarried woman complained of epigastralgia and nausea. X-ray examination showed narrowing of the antrum with granular appearance. On endoscopic examination large shallow ulcers and numerous irregular shaped polypoid masses were seen above the anglus to the antrum. Malignant lymphoma was suspected, however, the biopsy showed only mononuclear infiltration with no evidence of malignancy. There was no healing tendency of the lesion by using cimetidine, so it was suspected that the lesion may be gastric syphilis or tuberculosis. Based on a positive result of serologic test for syphilis, the anti-leuetic therapy was initiated. Her chief complaint was relieved and the gastroscopic findings were rapidly improved after the therapy. Therefore, this case was diagnosed as gastric syphilis. Gastric syphilis is relatively uncommon and it is difficult to distinguish from gastric malignant disease. It is important gastric syphilis should be considered in the differencial diagnosis of malignancy.
