A CASE OF PEUTZ-JEGHERS SYNDROME WHO HAD BEEN FOLLOWED FOR 27 YEARS BEFORE COLON CANCER DEVELOPED

Abstract

A 52-year-old male patient has been followed under the diagnosis of Peutz-Jeghers syndrome since 1961. He began to have abdominal pain, abdominal fullness, and constipation in January 1987. Sigmoidscopic examination disclosed a polypoid mass which irregulary constricted the lumen of the sigmoid colon. Insertion of sigmoidscope beyond the lesion was unsuccessful. Biopsy specimens obtained from the polyps revealed to well differenciated adenocarcinoma. Operation was performed on September 10, 1987. Macroscopically, the cancerous lesion was 4cm in length. To date, twenty-eight cases of Peutz-Jeghers syndrome who developed colon cancer have been reported in Japan. But there was no report on such long term follow-up case.