Abstract
A 77-year-old man was admitted to our hospital on October 12, 1987 because of hematemesis. Endoscopical examination showed multiple acute ulcers in the body of the stomach. These lesions were considered to occur due to the previous oral administration of an anti-inflamatory drug for treatment of neuralgia. Moreover, endoscopical examina-tion on the next day of his hospitalization showed a small fold-like lesion with redness in the antrum. He was treated medically and discharged from hospital in two weeks. On November 18, 1987, endoscopical examination showed that the ulcers healed to scars but a cancerous lesion of IIa+IIc type was located in the antrum. On December 9, 1989, endoscopical examination showed the cancer extremely grown in size and height of the protrusion and in depth of central depression. Operative resection was performed and it turned out to be a IIa+IIc type early cancer with submucosal invasion and intraepitherial multiple cysts, histologically moderately differentiated adenocarcinoma. This case showing rapid growth of cancer in only two months may give us many suggestions in the study on cancer development.
