COLITIS PRESENTING WITH LINEAR ULCER AND REDNESS WITH SPECIAL REFERRENCE TO COMPARISON OF ISCHEMIC AND ACTE HEMORRHAGIC COLITIS

Abstract

In a period of last 7 years, 59 of 185 cases with colitis had linear ulcer and redness. Of these, 49 cases of ischmic colitis (IC) or acute hemorrhagic colitis (AHC) were studied endoscopically and pathologically. We deviled AHC into 2 groups; the one group (D+) taking some drugs, especially antibiotics and the other (D-) not taking any drugs. There were 26 cases of D+, 9 cases of D-, and 14 cases of IC. Most of IC had ulcers and necrotic mucosa which endoscopically showed the most severe findings among these 3 groups. But in some cases of D+ group endoscopic findings were very similar to those of IC. The biopsied specimen taken within 3 days after the onset of colitis were examined in 27 cases. Degeneration of glands and goblet cell depletion of the mucosa were recognized in 70% of IC, while those were recognized in 58% even in D +. Therefore, the differential diagnosis between IC and D+ seems often difficult not only endoscopically but also pathologically. It was suggested that AHC after taking medicine would be induced by ischemia as well as IC.