Abstract
During a period of 17 years 222 proven pancreatic ductal adenocarcinomas have been studied. Male to female was 132 : 90, with an average age of 62 years. US was used as screening procedures. Should this be abnormal CT was performed. Large pancreatic car-cinomas were easily diagnosed with US and CT and preoperative staging was possible in majority of cases. However, ERCP was necessary in the diagno-sis of carcinoma smaller than 2cm. In all 21 car-cinomas smaller than 2cm ERCP showed abnormal-ity, but ductal change was relatively nonspecific. To establish the diagnosis angiography, "skinny" pan-creatoscopy and peroral ductal biopsy were rerfor-med. Cumulative life analysis of 4 patients with carcinoma smaller than 1 cm and limited to duct epithelium without parenchymal invasion revealed 100%. In those carcinomas larger than 2 cm with parenchymal invasion 5-year survival rate was less than 30%.