Abstract
We studied on 146 cases of gastric ulcer scar lesions endoscopicaly. We compared with the conventional endoscopic observation and color change after spraying 0.02% epine-phrine. At first, we classified conventional endoscopic stages, such as red scar stage (S1) to R1, R2 and R3 according to the redness, and white scar stage (S2) to W1 and W2. Color changes after spraying epinephrine were able to classify into whole redness (P1), partial redness (P2), and palness (P3). Color changes after pharmacoendoscopy were variable. In cases of chronic gastric ulcer, scar lesions showing strong redness remained redness even after spraying epinephrine. On the other hands, all lesions of the whitish scar (W2) changed to paleness (P3). But, in cases of scar lesins showing same color as surrounding mucosa (W1) changed altogether into P1, P2 and P3. Then, evaluation of the follow-up cases were performed. All acute ulcers after strip off biopsy were changed into P3 within 6 months. On the other hand, chronic ulcers were still observed P1 and P2 in over half cases after 12 months. Relapse cases showed S1, and S2. But, it was remained red in all cases after pharmacoendoscopy. Based on the results, we thought that pharmacoendoscopy was available for endoscopic determination of gastric ulcer healing.