Abstract
A 50-year-old male was admitted to our hospital because of fever and general fatigue. On the endoscopic examination, a tumor like lesion accompanied with ulceration was found in the posterior wall of the duodenal bulb. Histological examination revealed non-Hodgkin's lymphoma (diffuse large cell type). Computed tomography and bone scintigraphy were performed and revealed metastatic lesion in the liver, vertebrae, costal bone and iliac bone. The duodenal and liver lesions were disappeared with chemotherapy (VEPAM), bone lesions were not changed. Chemotherapy (ABEP) or irradiation were not effective for these lesions. Primary malignant lymphoma in duodenum is very rare. Only 46 cases were reported in literatures in Japan including our case.
