Abstract
We experienced 3 cases of gastric syphilis appearing ulcerative lesions in the corpus of the stomach. All of cases were not affective by administration of H2-blocker and showed strongly positive result of serologic test for syphilis. On the endoscopic examination, multiple ulcers with irregular shape were seen at the corpus and antrum in 3 cases. Immunofluorescent staining of the biopsy specimens in 2 cases was positive for Treponema pallidum in the gastric mucosa. Irregular ulcers of gastric syphilis develop due to ischemic change of gastric mucosa. They often develop at the antrum which shows the weak point of vascular structure and serious 3 cases extend to the corpus of the stomach.
