1992 Volume 34 Issue 3 Pages 541-545
The effect of abdominal insufflation (10mmHg) with carbon dioxide during laparo-scopic cholecystectomy (done under general anesthesia) on the circulatory and respiratory systems was investigated. Circulatory and respiratory parameters (Heart Rate, Arterial Blood pressure, etc) were serially measured in patients under the same respiratory, anesthetic and abdominal insufflation conditions. Out of the circulatory parameters, only central venous pressure significantly increased (p <0.01). Arterial blood pressure, heart rate, and cardiac output changed slightly. In terms of respiratory parameters, increases in endotracheal pressure and significant increase (p <0.01) in blood carbon dioxide concentra-tion occured. Values of these parameters tended to return to their pre-operative level following surgery. Central venous pressure and arterial carbon dioxide concentration tended to decrease after abdominal deflation ; however, they remained at significantly higher levels even after surgery. Such information on the changes that occur during anesthesia may allow this procedure to be conducted with greater safety.